What Is Ivermectin Injection?

Overview of Ivermectin Injection

Ivermectin injection is a macrolide antiparasitic drug, used primarily to treat various internal and external parasitic infections in animals, including heartworms, intestinal worms, mites, lice, etc. In appearance, it is often shown as colorless or almost colorless clear in liquid, slightly viscous.

 

How Does Ivermectin Work in Animals?

After injection, Ivermectin works by binding to and activating glutamate-gated chloride channels and other ligand-gated ion channels in the nerve and muscle cells of parasites. This action leads to paralysis and death of the parasites, effectively eliminating the infection.

 

Ivermectin Injection Uses in Veterinary Medicine

In veterinary medicine, ivermectin injection is widely used to treat a variety of parasitic infections in livestock and pets, including gastrointestinal worms and external parasites like lice and mites. For example:

Cattle: Gastrointestinal roundworms, Lungworms, Eye worms, Hypoderma bovis, Hypoderma lineatum, Mange mites, etc.

Sheep and Goats: Gastrointestinal roundworms, Lungworms, Eye worms, Hypoderma lineatum, Sheep nose bot larvae, Mange mites.

Pigs: Ascaris suum, Ancylostoma spp., Trichuris suis, Metastrongylus spp., Hematopinus suis, Sarcoptes scabiei, etc.

Horses: Strongylus spp., Strongyloides westeri, Bunostomum spp., Dictyocaulus arnfieldi, Haematopinus asini, Chorioptes equi, etc.

Cats and Dogs: Otodectes cynotis, Demodex cati, Dirofilaria immitis, Demodex canis, etc.

*Note: Ivermectin injection is not effective against flukes and tapeworms.

 

How is it Administered in Animals?

Ivermectin injection is typically administered subcutaneously (under the skin) or intramuscularly (into the muscle) in animals.

 

What is the Dosage of Ivermectin Injection in animals?

Dosage: The dosage of ivermectin injection varies based on the animal species, the type of parasite, and the animal’s weight. For example:

Cattle, goats, and sheep: 1 ml per 50 kg body weight.

Swine: 1 ml per 33 kg body weight.

Cats and dogs: 0.2 to 0.4 mg per kg body weight.

 

Side Effects of Ivermectin Injection When Used in Animals

As with all pharmaceuticals, some unwanted effects can occur from the use of Ivermectin injection.

Some common side effects may include pain or discomfort at the site of injection.

Serious side effects may include:

Lethargy, vomiting, gastrointestinal upset, ataxia (loss of coordination), and in rare cases, neurological symptoms.

 

Precautions and Contraindications When Using Ivermectin Injection

*Do use Ivermectin Injection for animals should pay attention to:

1. When used to treat psoriasis, if the killed larvae are in key parts, it will cause serious adverse reactions.

2. Discomfort or temporary edema will occur at the injection site during injection.

3. Each subcutaneous injection point should not exceed 10ml.

4. Caution is advised when using ivermectin in pregnant animals.

5. There are known interactions between this medication and other drugs, including benzodiazepines, ketamine, spinosad, amiodarone, carvedilol, clarithromycin, cyclosporine, and ketoconazole.

6. This drug may cause false-negative results for animals with an occult heartworm infection.

7. Ivermectin injection containing glycerol formal and propylene glycol is only suitable for cattle, sheep, and pigs.

8. Concomitant use with diethylcarbamazine may produce severe or fatal encephalopathy.

9. Ivermectin is highly toxic to shrimp, fish, and aquatic organisms. Do not allow residual drugs or packaging to contaminate water sources.

*Do NOT use Ivermectin Injection for animals that:

1. Do not use in cattle or sheep producing milk for human consumption.

2. Do not use in known cases of hypersensitivity to Ivermectin.

3. Do not use in lactating animals.

4. Do not use in a foal less than 4 months old or a puppy less than 6 weeks old.

5. Do not use in a dairy animal within 28 days of calving

6. Do not use in the following species: chelonian, Indigo snake, and skink

 

What is the Withdrawal Period for Ivermectin Injection?

– For meat

Calves, cattle, goats and sheep: 28 days.

Swine: 21 days.

– For milk:

Cows: 7 days.

Sheep: 7 days.

 

How Should Ivermectin Injection Be Stored?

This medication should be stored in a dark and dry location between 15-25°C.

Keep away from heat and direct sunlight. Exposure to heat or moisture may reduce the drug’s effectiveness.

The vial should be sealed tightly.

 

Conclusion

Ivermectin injection is an effective treatment for a range of parasitic infections in various animal species.

Gneebio has imported advanced production equipment, and first-class international inspection equipment, and has highly educated and experienced technicians to ensure quality stability and reliability of Ivermectin injection. Welcome to contact us today or request a quote.